Helicobacter – An Emerging New Zoonotic Pathogen
نویسنده
چکیده
The genus Helicobacter contains 35 named species and numerous provisionally named species. It is likely that several novel Helicobacter species await discovery. Members of this genus are microaerobic, have a fusiform or curved to spiral rod morphology and are motile by flagella that vary in number and location among different species (Vandamme et al., 1990). All known Helicobacters live in human and animal hosts, where colonization occurs primarily in the gastrointestinal tract. The type species, Helicobacter pylori (H. pylori), was isolated from the stomach of humans and has been associated with a variety of gastric anomalies including gastritis, peptic ulcer disease, gastric carcinoma, and gastric mucosaassociated lymphoma (Parsonnet, 1998). Like H. pylori, other species of Helicobacter have also been shown to colonize the stomach and cause disease in animals. Gastric colonizers include H. felis, H. mustelae, H. acinonychis, H. bizzozeronii, H. heilmannii, H. salomonis, and a recently isolated novel Helicobacter sp. of dolphins (Hodzic et al., 2001). Several species of Helicobacter have been identified in rodents, including the species H. hepaticus, H. bilis, H. muridarum, H. aurati, H. cinaedi, H. cholecystus, H. trogontum, H. rodentium, and a bacterium morphologically resembling H. Flexispira taxon 8 (formerly Flexispira rappini) (Hodzic et al., 2001). Evidence is accumulating that especially pigs, dogs, and cats constitute reservoir hosts for gastric Helicobacter species with zoonotic potential.
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تاریخ انتشار 2012